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Table 15. Evaluation of False Negative Error Rate of the ROI Algorithm


Radionuclide

Photon Energy (keV)

Equivalent Human Body Burden  (c s-1)

Typical Human a LC (c s-1)

Body Burden relative to LC

Observed False Negative Rate (%)

212Pb
2.4E+02
6.4E-03
8.7E-03
0.73
68.3
228Ac
8.4E+02
4.4E-03
1.1E-02
0.39
87.0
228Ac
9.1E+02
5.8E-03
1.1E-02
0.53
63.2
60Co
1.3E+03
9.5E-03
9.6E-03
1.00
43.0
aTheoretically, if a subject had a body burden equal to LC, the detection of that radionuclide at LC would be missed when actually present (false negative) 50% of the time. The false negative error rate would then increase as the body burden becomes smaller relative to LC until eventually no activity would be detected.